BDBM328004 5-(4-(4- carbamoylbenzyl) piperidine-1-carbonyl)- N-(1-(4- cyanobenzyl)piperidin-4- yl)picolinamide::US9663496, Compound 141

SMILES NC(=O)c1ccc(CC2CCN(CC2)C(=O)c2ccc(nc2)C(=O)NC2CCN(Cc3ccc(cc3)C#N)CC2)cc1

InChI Key InChIKey=VEVULXHDAOOWBK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328004   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328004(US9663496, Compound 141 | 5-(4-(4- carbamoylbenzyl...)
Affinity DataEC50:  750nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent