BDBM328013 N-(trans-4-(4- cyanophenoxy) cyclohexyl)-5-(4-(4- fluorobenzoyl) piperazine-1- carbonyl)picolinamide::US10377742, Compound 151::US9663496, Compound 151

SMILES Fc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(nc1)C(=O)N[C@H]1CC[C@H](CC1)Oc1ccc(cc1)C#N

InChI Key InChIKey=KILULKZXXSWNCI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328013   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328013(US9663496, Compound 151 | N-(trans-4-(4- cyanophen...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328013(US9663496, Compound 151 | N-(trans-4-(4- cyanophen...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent