BDBM328048 N-((cis)-4-(4- methoxyphenoxy) cyclohexyl)-5-(4-(4- methoxyphenoxy) piperidine-1- carbonyl)picolinamide::US10377742, Compound 186::US9663496, Compound 186

SMILES COc1ccc(O[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(cn2)C(=O)N2CCC(CC2)Oc2ccc(OC)cc2)cc1

InChI Key InChIKey=KNSGWXFUNINQIP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328048   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328048(US9663496, Compound 186 | N-((cis)-4-(4- methoxyph...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328048(US9663496, Compound 186 | N-((cis)-4-(4- methoxyph...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent