BDBM328075 6-(4-(2,4- difluorobenzoyl) piperidine-1-carbonyl)- N-(1-(4- (methylsulfonyl)benzyl) piperidin-4- yl)nicotinamide::US10377742, Compound 213::US9663496, Compound 213

SMILES CS(=O)(=O)c1ccc(CN2CCC(CC2)NC(=O)c2ccc(nc2)C(=O)N2CCC(CC2)C(=O)c2ccc(F)cc2F)cc1

InChI Key InChIKey=FXHBRSQJDSUPGH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328075   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328075(US9663496, Compound 213 | 6-(4-(2,4- difluorobenzo...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328075(US9663496, Compound 213 | 6-(4-(2,4- difluorobenzo...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent