BDBM328138 N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(1-(4- fluorophenyl)piperidin- 4-ylamino)picolinamide::US10377742, Compound 276::US9663496, Compound 276

SMILES Fc1ccc(cc1)N1CCC(CC1)Nc1ccc(nc1)C(=O)NC1CCN(Cc2ccc(cc2)C#N)CC1

InChI Key InChIKey=WDIUOLAJMWXWDH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328138   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328138(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(1-(4- flu...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328138(N-(1-(4- cyanobenzyl)piperidin-4- yl)-5-(1-(4- flu...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent