BDBM328829 (S)-4-((2- (cyclopropanesulfonamidomethyl)-6- ((((1,1,1-trifluoro-2-methylpropan-2- yl)oxy)carbonyl)amino)-2H- benzo[b][1,4]oxazin-4(3H)- yl)sulfonyl)-3-(difluoromethoxy)-1- ethyl-1H-pyrazole::US9663502, 36Y

SMILES CCn1cc(c(OC(F)F)n1)S(=O)(=O)N1C[C@H](CNS(=O)(=O)C2CC2)Oc2ccc(NC(=O)OC(C)(C)C(F)(F)F)cc12

InChI Key InChIKey=FBQOQONGQMOHFK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328829   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM328829(US9663502, 36Y | (S)-4-((2- (cyclopropanesulfonami...)
Affinity DataIC50: 5.83nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent