BDBM33070 4-(2,3-dihydro-1H-perimidin-2-yl)-2-ethoxy-phenol::4-(2,3-dihydro-1H-perimidin-2-yl)-2-ethoxyphenol::MLS000068595::SMR000122974::cid_760604

SMILES CCOc1cc(ccc1O)C1Nc2cccc3cccc(N1)c23

InChI Key InChIKey=VPSWFBIJAAALET-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 33070   

TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33070(4-(2,3-dihydro-1H-perimidin-2-yl)-2-ethoxy-phenol ...)
Affinity DataEC50:  3.76E+4nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33070(4-(2,3-dihydro-1H-perimidin-2-yl)-2-ethoxy-phenol ...)
Affinity DataEC50:  3.17E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAndrogen receptor(Homo sapiens (Human))
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM33070(4-(2,3-dihydro-1H-perimidin-2-yl)-2-ethoxy-phenol ...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of human AR AF2 site expressed in human LNCap cells coexpressing eGFP -ARR2PB assessed as inhibition of transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM33070(4-(2,3-dihydro-1H-perimidin-2-yl)-2-ethoxy-phenol ...)
Affinity DataIC50:  3.15E+4nMAssay Description:Displacement of SRC2-3 peptide from human AR ligand binding site expressed in Escherichia coli BL21 by AF2 FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 55(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33070(4-(2,3-dihydro-1H-perimidin-2-yl)-2-ethoxy-phenol ...)
Affinity DataEC50:  8.01E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay