BDBM331627 Preparation of 2-(4-(6,7-dimethoxyquinoxalin-2-yl)phenyl)-N-(5-(1-(trifluoromethyl)cyclopropyl)isoxazol-3-yl)acetamide::US9725465, Example 1

SMILES COc1cc2ncc(nc2cc1OC)-c1ccc(CC(=O)Nc2cc(on2)C2(CC2)C(F)(F)F)cc1

InChI Key InChIKey=YJQLIMNVKRIHMJ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331627   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM331627(Preparation of 2-(4-(6,7-dimethoxyquinoxalin-2-yl)...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM331627(Preparation of 2-(4-(6,7-dimethoxyquinoxalin-2-yl)...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent