BDBM331655 Preparation of 2-(4-(2,3-dihydro-[1,4]dioxino[2,3-g]quinoxalin-7-yl)-2-fluorophenyl)-N-(5-(1-(trifluoromethyl)cyclopropyl)isoxazol-3-yl)acetamide::US9725465, Example 76

SMILES Fc1cc(ccc1CC(=O)Nc1cc(on1)C1(CC1)C(F)(F)F)-c1cnc2cc3OCCOc3cc2n1

InChI Key InChIKey=YQHICSNVABYXJV-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331655   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM331655(Preparation of 2-(4-(2,3-dihydro-[1,4]dioxino[2,3-...)
Affinity DataKd:  12.5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM331655(Preparation of 2-(4-(2,3-dihydro-[1,4]dioxino[2,3-...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent