BDBM33183 5-[[5-(5-chloranyl-2-nitro-phenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione::5-[[5-(5-chloro-2-nitro-phenyl)-2-furyl]methylene]barbituric acid::5-[[5-(5-chloro-2-nitrophenyl)-2-furanyl]methylidene]-1,3-diazinane-2,4,6-trione::5-[[5-(5-chloro-2-nitrophenyl)furan-2-yl]methylidene]-1,3-diazinane-2,4,6-trione::MLS000689180::SMR000283261::cid_3122089

SMILES [O-]c1[nH]c(=O)[nH]c(=O)c1[CH+]c1ccc(o1)-c1cc(Cl)ccc1[N+]([O-])=O

InChI Key InChIKey=YYYIFMQBWXLXQE-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 33183   

TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33183(5-[[5-(5-chloranyl-2-nitro-phenyl)furan-2-yl]methy...)
Affinity DataEC50:  1.24E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33183(5-[[5-(5-chloranyl-2-nitro-phenyl)furan-2-yl]methy...)
Affinity DataIC50:  3.33E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33183(5-[[5-(5-chloranyl-2-nitro-phenyl)furan-2-yl]methy...)
Affinity DataIC50:  4.58E+3nMAssay Description:Data Source: Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute Network...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33183(5-[[5-(5-chloranyl-2-nitro-phenyl)furan-2-yl]methy...)
Affinity DataEC50:  810nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33183(5-[[5-(5-chloranyl-2-nitro-phenyl)furan-2-yl]methy...)
Affinity DataEC50:  2.64E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 10 [11-204](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33183(5-[[5-(5-chloranyl-2-nitro-phenyl)furan-2-yl]methy...)
Affinity DataEC50:  3.65E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay