BDBM33217 pyrazolopyridine, (S)-14

SMILES NC[C@H]1CN(CCO1)c1c(cnc2[nH]ncc12)-c1ccccc1

InChI Key InChIKey=YBRZCAKSBYWZTC-ZDUSSCGKSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 33217   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

LigandPNGBDBM33217(pyrazolopyridine, (S)-14)
Affinity DataIC50:  860nMpH: 7.5 T: 2°CAssay Description:CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...More data for this Ligand-Target Pair