BDBM333146 Compound I::US10196404, Example 1::US10196404, Example 2::US10196404, Example 3::US11472816, Example 3::US11691989, Compound AZD5991

SMILES: Cc1c-2c(CSCc3cc(CSc4cc(OCCCc5c(C(O)=O)n(C)c6c-2c(Cl)ccc56)c2ccccc2c4)n(C)n3)nn1C

InChI Key: InChIKey=KBQCEQAXHPIRTF-UHFFFAOYSA-N

Data: 5 KI  15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 333146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
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Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-like protein 2 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-related protein A1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-like protein 1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
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Apoptosis regulator Bcl-2 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-like protein 1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-323] (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM333146 (US10196404, Example 1 | Compound I | US10196404, E...) Show SMILES Show InChI	GoogleScholar	UniChem		170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair