BDBM333658 1-{3-[6- methoxy-7- (2- methoxyethoxy) quinazolin- 4-yloxy] phenyl}-3- [1- methyl-5- (trifluoromethyl)- 1H-pyrazol-3-yl] urea::US9730937, Example 208
SMILES COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(n(C)n4)C(F)(F)F)c3)c2cc1OC
InChI Key InChIKey=DIDCGAFNOVPPMS-UHFFFAOYSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 333658
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
US Patent
Ambit Biosciences
US Patent
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair