BDBM333744 1-(5-(1,3- difluoro-2- methylpropan-2- yl)isoxazol- 3-yl)-3- (3-(6,7- dimethoxy- quinazolin- 4- yloxy)-4- fluorophenyl)u rea::US9730937, Example 294
SMILES COc1cc2ncnc(Oc3cc(NC(=O)Nc4cc(on4)C(C)(CF)CF)ccc3F)c2cc1OC
InChI Key InChIKey=QBPFTEHJMUAEBL-UHFFFAOYSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 333744
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
US Patent
Ambit Biosciences
US Patent
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair