BDBM33410 CHEMBL16755::N-hydroxyisoquinolinedione, 2::US20250213569, Compound 13

SMILES: c1ccc2c(c1)CC(=O)N(C2=O)O

InChI Key: InChIKey=ZXAICCBFIBBVAR-UHFFFAOYSA-N

Data: 1 KI  13 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 33410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	135	n/a	n/a	n/a	n/a	8.0	20
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Replicase polyprotein 1ab (2019-nCoV)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
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Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.22E+3	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM33410 (CHEMBL16755 | N-hydroxyisoquinolinedione, 2 | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair