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BDBM3345 4-N-[(3-aminophenyl)methyl]pyrido[4,3-d]pyrimidine-4,7-diamine::7-Aminopyrido[4,3-d]pyrimidine 8o::7-amino-4-[[(3-aminophenyl)methyl]amino]pyrido[4,3-d]pyimidine

SMILES: Nc1cccc(CNc2ncnc3cc(N)ncc23)c1

InChI Key: InChIKey=FIDYSXSIFTWCGR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3345   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM3345
PNG
(4-N-[(3-aminophenyl)methyl]pyrido[4,3-d]pyrimidine...)
Show SMILES Nc1cccc(CNc2ncnc3cc(N)ncc23)c1
Show InChI InChI=1S/C14H14N6/c15-10-3-1-2-9(4-10)6-18-14-11-7-17-13(16)5-12(11)19-8-20-14/h1-5,7-8H,6,15H2,(H2,16,17)(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Auckland



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...


J Med Chem 38: 3780-8 (1995)


Article DOI: 10.1021/jm00019a007
BindingDB Entry DOI: 10.7270/Q2Z899M8
More data for this
Ligand-Target Pair