BDBM334889 US11040966, Example 5.155::US9732075, Example 5.155::[(S)-2-(6-Chloro-5-trifluoromethyl-1H-benzoimidazol-2-yl)-2-methyl-pyrrolidin-1-yl]-(4-methyl-3'-trifluoromethyl-biphenyl-2-yl)-methanone

SMILES Cc1ccc(-c2cccc(c2)C(F)(F)F)c(c1)C(=O)N1CCC[C@@]1(C)c1nc2cc(c(Cl)cc2[nH]1)C(F)(F)F

InChI Key InChIKey=CCDLLBNMKKXVND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 334889   

TargetOrexin/Hypocretin receptor type 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334889(US9732075, Example 5.155 | [(S)-2-(6-Chloro-5-trif...)
Affinity DataIC50: 134nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334889(US9732075, Example 5.155 | [(S)-2-(6-Chloro-5-trif...)
Affinity DataIC50: 249nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent