BDBM335008 US11040966, Example 5.69::US9732075, Example 5.69::[(S)-2-(5,6-Dimethoxy-1H-benzoimidazol-2-yl)-2-methyl-pyrrolidin-1-yl]-(2-fluoro-3-methoxy-6-[1,2,3]triazol-2-yl-phenyl)-methanone

SMILES COc1ccc(c(C(=O)N2CCC[C@@]2(C)c2nc3cc(OC)c(OC)cc3[nH]2)c1F)-n1nccn1

InChI Key InChIKey=VCGDWTXNEHVLAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335008   

TargetOrexin/Hypocretin receptor type 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335008(US9732075, Example 5.69 | [(S)-2-(5,6-Dimethoxy-1H...)
Affinity DataIC50: 414nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335008(US9732075, Example 5.69 | [(S)-2-(5,6-Dimethoxy-1H...)
Affinity DataIC50: 1.20E+3nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent