BDBM33514 2-(2-bromophenyl)-5-[(5-methyl-2-furanyl)methylidene]-6-thiazolo[3,2-b][1,2,4]triazolone::2-(2-bromophenyl)-5-[(5-methyl-2-furyl)methylene]thiazolo[3,2-b][1,2,4]triazol-6-one::2-(2-bromophenyl)-5-[(5-methylfuran-2-yl)methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one::MLS000039533::SMR000034950::cid_662189

SMILES Cc1ccc(C=c2sc3nc(nn3c2=O)-c2ccccc2Br)o1

InChI Key InChIKey=BVUAQJINEZJNCE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 33514   

TargetEstrogen receptor beta(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33514(cid_662189 | 2-(2-bromophenyl)-5-[(5-methylfuran-2...)
Affinity DataIC50: 61.1nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
LigandPNGBDBM33514(cid_662189 | 2-(2-bromophenyl)-5-[(5-methylfuran-2...)
Affinity DataIC50: 3.18E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
LigandPNGBDBM33514(cid_662189 | 2-(2-bromophenyl)-5-[(5-methylfuran-2...)
Affinity DataIC50: 5.95E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2012
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33514(cid_662189 | 2-(2-bromophenyl)-5-[(5-methylfuran-2...)
Affinity DataIC50: 8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetProthrombin(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33514(cid_662189 | 2-(2-bromophenyl)-5-[(5-methylfuran-2...)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2009
Entry Details
PCBioAssay
TargetEstrogen receptor beta(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM33514(cid_662189 | 2-(2-bromophenyl)-5-[(5-methylfuran-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetM17 leucyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33514(cid_662189 | 2-(2-bromophenyl)-5-[(5-methylfuran-2...)
Affinity DataIC50: 9.55E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay