BDBM336588 4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(5-methyloxazol-2-yl)-1H-indazol-3-yl)benzoate::US9745265, 9A

SMILES Cc1cnc(o1)-c1ccc2c(nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c2c1)-c1ccc(cc1)C([O-])=O

InChI Key InChIKey=QZUPDRDWKANKTI-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336588   

TargetNuclear receptor ROR-gamma(Mus musculus)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336588(4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(5-me...)
Affinity DataIC50:  63nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent