BDBM3375 7-{2-chloro-5-ethylimidazo[1,5-a]pyridazin-7-yl}-1-phenylheptan-1-one::Imidazopyridazine 17c

SMILES CCc1nc(CCCCCCC(=O)c2ccccc2)n2nc(Cl)ccc12

InChI Key InChIKey=HYXAKSPXUBIKLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3375   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandPNGBDBM3375(7-{2-chloro-5-ethylimidazo[1,5-a]pyridazin-7-yl}-1...)
Affinity DataIC50:  2.00E+3nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed