BDBM337703 3-(2-Chloro-3-(trifluoromethyl)benzyl)-1-[3,5-difluoro-4-(2-oxoimidazolidin-1-yl)phenyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid::US9751843, 77

SMILES OC(=O)c1cn(-c2cc(F)c(N3CCNC3=O)c(F)c2)c(=O)n(Cc2cccc(c2Cl)C(F)(F)F)c1=O

InChI Key InChIKey=JHWJPWVMHJGGTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337703   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337703(3-(2-Chloro-3-(trifluoromethyl)benzyl)-1-[3,5-difl...)
Affinity DataIC50:  97nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent