BDBM337778 3-[2-Chloro-3-(trifluoromethyl)benzyl]-1-[4-(3-methyl-2-oxoimidazolidin-1-yl)phenyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid::US9751843, 171

SMILES CN1CCN(C1=O)c1ccc(cc1)-n1cc(C(O)=O)c(=O)n(Cc2cccc(c2Cl)C(F)(F)F)c1=O

InChI Key InChIKey=XWDYOCDMQLVPDW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337778   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337778(3-[2-Chloro-3-(trifluoromethyl)benzyl]-1-[4-(3-met...)
Affinity DataIC50:  370nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent