BDBM338325 (4-{1-[3-Fluoro-4-((3S,6R)-3- methyl-1,1-dioxo-6-phenyl- [1,2]thiazinan-2-ylmethyl)-phenyl]- piperidin-4-yl}-4H-[1,2,4]triazol-3- yl)-acetonitrile::US9751873, Example 11

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1ccc(cc1F)N1CCC(CC1)n1cnnc1CC#N

InChI Key InChIKey=LTQOZPCBXLBQDA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338325   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338325((4-{1-[3-Fluoro-4-((3S,6R)-3- methyl-1,1-dioxo-6-p...)
Affinity DataIC50: 420nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
US Patent