BDBM338332 (1S,5R,6S)-3-[2,3-Difluoro-4- ((3S,6R)-3-methyl-1,1-dioxo-6- phenyl-[1,2]thiazinan-2-ylmethyl)- phenyl]-6-[1,2,4]triazol-4-yl-3-aza- bicyclo[3.1.0]hexane::US9751873, Example 18

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1ccc(N2C[C@H]3[C@@H](C2)[C@@H]3n2cnnc2)c(F)c1F

InChI Key InChIKey=RPISIIHHVYMFLF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338332   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM338332((1S,5R,6S)-3-[2,3-Difluoro-4- ((3S,6R)-3-methyl-1,...)
Affinity DataIC50: 44nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
US Patent