BDBM338927 (E)-3-(3-(2,6-bis(trifluoromethyl)styryl)- phenyl)propan-1-amine::US10201545, Compound 49

SMILES: NCCCc1cccc(\C=C\c2c(cccc2C(F)(F)F)C(F)(F)F)c1

InChI Key: InChIKey=NGNAJYMEOALPDA-MDZDMXLPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinaldehyde-binding protein 1 (Homo sapiens (Human))	BDBM338927 ((E)-3-(3-(2,6-bis(trifluoromethyl)styryl)- phenyl)...) Show SMILES NCCCc1cccc(\C=C\c2c(cccc2C(F)(F)F)C(F)(F)F)c1 Show InChI InChI=1S/C19H17F6N/c20-18(21,22)16-7-2-8-17(19(23,24)25)15(16)10-9-14-5-1-4-13(12-14)6-3-11-26/h1-2,4-5,7-10,12H,3,6,11,26H2/b10-9+	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ACUCELA INC. US Patent					Assay Description The isomerase assay was performed in 10 mM bis-tris-propane (BTP) buffer, pH 7.5, 0.5% BSA (diluted in BTP buffer), 1 mM sodium pyrophosphate, 20 ...				US Patent US10201545 (2019) BindingDB Entry DOI: 10.7270/Q2JS9SJM
					More data for this Ligand-Target Pair