BDBM33932 4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-dienone::4-(3H-1,3-benzothiazol-2-ylidene)cyclohexa-2,5-dien-1-one::CHEMBL47875::MLS000773814::SMR000364661::cid_5351155

SMILES Oc1ccc(cc1)-c1nc2ccccc2s1

InChI Key InChIKey=ODMDLCWSMSFWCW-UHFFFAOYSA-N

Data  2 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 33932   

TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataKi:  567nMAssay Description:Inhibition of mushroom tyrosinase at 1.25 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of mushroom tyrosinase at 20 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of bovine liver beta glucuronidase assessed as p-nitrophenol formation after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor receptor superfamily member 10B(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataEC50: >1.25E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProthrombin(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataIC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed