BDBM33971 AEB071::Sotrastaurin::med.21724, Compound 190

SMILES: CN1CCN(CC1)c1nc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc2n1

InChI Key: InChIKey=OAVGBZOFDPFGPJ-UHFFFAOYSA-N

Data: 1 KI  41 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 43 hits for monomerid = 33971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C eta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C eta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Rat)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	234	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.4	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C eta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orf1a protein (MERS-CoV)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D3 (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.4	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C eta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM33971 (Sotrastaurin | AEB071 | med.21724, Compound 190) Show SMILES Show InChI	GoogleScholar	UniChem		2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair