BDBM340077 (S,E)-4-(8-amino-3-(1-but-2- enoylpyrrolidin-2-yl)imidazo[1,5- a]pyrazin-1-yl)-N-(pyridin-2- yl)benzamide::US10239883, Example 93::US10934296, Example 93::US9758524, Example 93

SMILES: C\C=C\C(=O)N1CCC[C@H]1c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12

InChI Key: InChIKey=VSFINVOSLLRTIP-UHFFFAOYSA-N

Data: 15 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 340077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>100	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lyn (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lyn (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lyn (Human)	BDBM340077 (US9758524, Example 93 | (S,E)-4-(8-amino-3-(1-but-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair