BDBM340511 US9763922, Example 42

SMILES CC(=O)N1CCC(NCC2CC2)=C(C1)C(=N)Nc1ccc(nc1)-c1cnn(C)c1

InChI Key InChIKey=FUELDHFJOFMFOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340511   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM340511(US9763922, Example 42)
Affinity DataIC50: 30nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Genentech

US Patent
LigandPNGBDBM340511(US9763922, Example 42)
Affinity DataIC50: 3.29E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent