BDBM34080 benzamide derivative, 13h

SMILES Cn1ccnc1Sc1cc(C(=O)Nc2cccc(c2)C(F)(F)F)c(N)cc1F

InChI Key InChIKey=CZZSDGPOOCLEEH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34080   

TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Shanghai Institutes For Biological Sciences

LigandPNGBDBM34080(benzamide derivative, 13h)
Affinity DataIC50:  8.95E+3nMpH: 7.2 T: 2°CAssay Description:The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Shanghai Institutes For Biological Sciences

LigandPNGBDBM34080(benzamide derivative, 13h)
Affinity DataEC50:  1.87E+3nMAssay Description:The GK activity was assessed spectrometrically by a coupled reaction with glucose-6-phosphate dehydrogenase (G6PDH). Briefly, GK catalyzes glucose ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed