BDBM341103 1-{5-Chloro-2-[(3S)-3-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]phenyl}-N-(4-hydroxyphenyl)-N-phenyl-1H-indole-3-carboxamide::US9765056, Example 171

SMILES Oc1ccc(cc1)N(C(=O)c1cn(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCCCC2)c2ccccc12)c1ccccc1

InChI Key InChIKey=WEPSYOHJWXWESK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341103   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM341103(US9765056, Example 171 | 1-{5-Chloro-2-[(3S)-3-(pi...)
Affinity DataIC50: 71.8nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
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Date in BDB:
7/29/2019
Entry Details
US Patent