BDBM341657 2-(2-ethyl-4-fluorophenoxy)-1-(5-(2-fluoro-4-methyl-phenyl)-7,8-dihydrothiazolo[2',3':2,3]imidazo[4,5-c]-pyridin-6(5H)-yl)ethanone::US9765092, Example 6.10.4

SMILES CCc1cc(F)ccc1OCC(=O)N1CCc2nc3sccn3c2C1c1ccc(C)cc1F

InChI Key InChIKey=IYMAFIRQTJKLMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341657   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM341657(2-(2-ethyl-4-fluorophenoxy)-1-(5-(2-fluoro-4-methy...)
Affinity DataIC50:  6nMAssay Description:To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent