BindingDB PrimarySearch

BDBM34168 LOVASTATIN::MLS000069585::SMR000058779::US9115116, lovastatin::US9353061, Lovastatina::cid_53232

SMILES: CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12

InChI Key: InChIKey=PCZOHLXUXFIOCF-UHFFFAOYSA-N

Data: 4 KI 41 IC50 1 Kd 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 47 hits for monomerid = 34168
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-dependent translocase ABCB1 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
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Lanosterol 14-alpha demethylase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B1 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Integrin alpha-L/beta-2 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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ATP-dependent translocase ABCB1 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Integrin alpha-L (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 2 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Histone deacetylase 1 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Bile salt export pump (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Bcl-2-related protein A1 (Mouse)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	29.5	n/a	n/a	n/a	n/a	7.4	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 1 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	25
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Histone deacetylase 2 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.59E+4	n/a	n/a	n/a	n/a	n/a	25
TBA								Citation and Details
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Histone deacetylase 6 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	25
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Cystic fibrosis transmembrane conductance regulator (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	29.5	n/a	n/a	n/a	n/a	7.4	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 1 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	25
TBA								Citation and Details
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Histone deacetylase 2 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.59E+4	n/a	n/a	n/a	n/a	n/a	25
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Histone deacetylase 6 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	25
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Mouse)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.0	23
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ATP-binding cassette sub-family C member 2 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Intercellular adhesion molecule 1 (Human)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Horse)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Horse)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM34168 (cid_53232 \| SMR000058779 \| MLS000069585 \| LOVASTAT...) Show SMILES Show InChI	GoogleScholar	UniChem	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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