BindingDB PrimarySearch

BDBM34233 2-Phenyl-benzo[d]isoselenazol-3-one::2-Phenyl-benzo[d]isoselenazol-3-one(Ebselen)::2-phenyl-1,2-benzisoselazol-3(2H)-one::2-phenyl-1,2-benzoselenazol-3-one::2-phenylbenzo[d][1,2]selenazol-3(2H)-one::CHEMBL51085::EBSELEN::Ebselen (C5)::MLS000028488::SMR000058445::cid_3194::med.21724, Compound 153

SMILES: O=c1n([se]c2ccccc12)-c1ccccc1

InChI Key: InChIKey=DYEFUKCXAQOFHX-UHFFFAOYSA-N

Data: 14 KI 95 IC50 2 Kd 6 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 115 hits for monomerid = 34233
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gag-Pol polyprotein (HIV-1)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	8.0	23
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Mannose-6-phosphate isomerase (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<391	n/a	n/a	n/a	n/a	7.4	23
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Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	485	n/a	n/a	n/a	n/a	n/a	n/a
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Diphosphomevalonate decarboxylase (Streptococcus pneumoniae D39)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	513	n/a	n/a	n/a	n/a	n/a	n/a
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Mevalonate kinase (Streptococcus pneumoniae D39)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	287	n/a	n/a	n/a	n/a	n/a	n/a
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Mevalonate kinase (Streptococcus pneumoniae D39)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Mevalonate kinase (Streptococcus pneumoniae D39)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-directed RNA polymerase subunit beta (Escherichia coli)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mannose-6-phosphate isomerase (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphotransferase (Trypanosoma brucei brucei (strain 927/4 GUTat10.1))	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	901	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphomannomutase 2 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	672	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphoethanolamine/phosphocholine phosphatase (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 4 gamma 1 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
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dTDP-4-dehydrorhamnose 3,5-epimerase (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Neutrophil cytosol factor 1 [S99G] (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
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Large T antigen (SV40)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitochondrial import inner membrane translocase subunit TIM10 (Baker's yeast)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Perilipin-1 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Perilipin-5 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitochondrial import inner membrane translocase subunit TIM23 (Baker's yeast)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
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Hexokinase HKDC1 [W721R] (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.88E+4	n/a	n/a	n/a	n/a
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Hexokinase-1 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	4.19E+4	n/a	n/a	n/a	n/a
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Beta-arrestin-1 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
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UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Haemophilus influenzae (G-proteobacteria))	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Genome polyprotein (Hepacivirus C)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.5	23
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Caspase-1 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.04E+3	n/a	n/a	n/a	n/a	7.5	25
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Replicase polyprotein 1ab (2019-nCoV)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	4.67E+3	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	4.67E+3	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
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Histone-lysine N-methyltransferase EHMT1 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage migration inhibitory factor (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
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Sulfhydryl oxidase 1 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 5 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 9 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Toxin B (Peptoclostridium difficile)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-degrading enzyme (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-degrading enzyme (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-degrading enzyme (Human)	BDBM34233 (EBSELEN \| 2-Phenyl-benzo[d]isoselenazol-3-one(Ebse...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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