BDBM342573 1-(1,3-benzodioxol-5-yl)-3-methyl-2,5,6,7-tetrahydro-4H-isoindol-4-one::US9776990, Example 16

SMILES Cc1[nH]c(c2CCCC(=O)c12)-c1ccc2OCOc2c1

InChI Key InChIKey=IWSOERZTQGUJBE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342573   

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM342573(1-(1,3-benzodioxol-5-yl)-3-methyl-2,5,6,7-tetrahyd...)
Affinity DataKi:  3.77E+3nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM342573(1-(1,3-benzodioxol-5-yl)-3-methyl-2,5,6,7-tetrahyd...)
Affinity DataKi:  8.42E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent