BDBM342658 5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-piperazin-1-ylmethyl]-4-methyl-thiophene-2-carboxylic acid (3,3-dimethyl-butyl)-amide::US9776991, Example 159::US9776991, Example 28

SMILES Cc1cc(sc1CN1CCN(CC1)C(=O)c1c(C)cc(=O)oc1C)C(=O)NCCC(C)(C)C

InChI Key InChIKey=GRPCQSWPQHWHSX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342658   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM342658(5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-pipe...)
Affinity DataIC50:  0.800nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM342658(5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-pipe...)
Affinity DataIC50:  0.803nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent