BDBM342665 5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-piperazin-1-ylmethyl]-thiophene-2-carboxylic acid 2-trifluoromethoxy-benzylamide::US9776991, Example 35

SMILES Cc1cc(=O)oc(C)c1C(=O)N1CCN(Cc2ccc(s2)C(=O)NCc2ccccc2OC(F)(F)F)CC1

InChI Key InChIKey=VPYLPRZRDMTEEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342665   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM342665(5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-pipe...)
Affinity DataIC50:  0.916nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent