BDBM34275 4-(1,3-benzodioxol-5-yl)-3-methyl-1-(4-methylphenyl)-2,4-dihydropyrazolo[3,4-e][1,4]thiazepin-7-one::4-(1,3-benzodioxol-5-yl)-3-methyl-1-(p-tolyl)-2,4-dihydropyrazolo[3,4-e][1,4]thiazepin-7-one::MLS000082564::SMR000046179::cid_5389923

SMILES Cc1nn(c2NC(=O)CSC(c12)c1ccc2OCOc2c1)-c1ccc(C)cc1

InChI Key InChIKey=OOFJLPXTMMWITI-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 34275   

TargetGag-Pol polyprotein(HIV-1)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM34275(cid_5389923 | 4-(1,3-benzodioxol-5-yl)-3-methyl-1-...)
Affinity DataIC50: 5.20E+3nMpH: 8.0 T: 2°CAssay Description:A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2009
Entry Details
PCBioAssay
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM34275(cid_5389923 | 4-(1,3-benzodioxol-5-yl)-3-methyl-1-...)
Affinity DataEC50:  6.71E+3nMAssay Description:Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM34275(cid_5389923 | 4-(1,3-benzodioxol-5-yl)-3-methyl-1-...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay