BDBM342765 N-Methyl-2-{4-[5-(2-trifluoromethoxy-benzylcarbamoyl)-thiophen-2-ylmethyl]-piperazin-1-yl}-nicotinamide::US9776991, Example 135

SMILES CNC(=O)c1cccnc1N1CCN(Cc2ccc(s2)C(=O)NCc2ccccc2OC(F)(F)F)CC1

InChI Key InChIKey=XTBNICZGKYZCTO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342765   

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandPNGBDBM342765(N-Methyl-2-{4-[5-(2-trifluoromethoxy-benzylcarbamo...)
Affinity DataIC50: 2.14nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent