BDBM342845 1-(6-(bis(2-methylpropyl)amino)-2-methoxy-3-pyridinyl)-N-4-pyrimidinyl-6-isoquinolinesulfonamide::US9776995, Example 46

SMILES COc1nc(ccc1-c1nccc2cc(ccc12)S(=O)(=O)Nc1ccncn1)N(CC(C)C)CC(C)C

InChI Key InChIKey=MIXROGFKLGZQBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342845   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM342845(1-(6-(bis(2-methylpropyl)amino)-2-methoxy-3-pyridi...)
Affinity DataIC50:  1.36E+4nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent