BDBM342871 1-(4'-chloro-2-fluoro-5-methoxy-3'-methyl-4-biphenylyl)-N-3-pyridazinyl-6-isoquinolinesulfonamide::US9776995, Example 87

SMILES COc1cc(c(F)cc1-c1nccc2cc(ccc12)S(=O)(=O)Nc1cccnn1)-c1ccc(Cl)c(C)c1

InChI Key InChIKey=FJTZWFRBQYPDFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342871   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM342871(1-(4'-chloro-2-fluoro-5-methoxy-3'-methyl-4-biphen...)
Affinity DataIC50:  178nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent