BDBM342937 1-(6-cyano-3',5'-difluoro-4-methoxy-3-biphenylyl)-N-4-pyrimidinyl-6-isoquinolinesulfonamide::US9776995, Example 145

SMILES COc1cc(C#N)c(cc1-c1nccc2cc(ccc12)S(=O)(=O)Nc1ccncn1)-c1cc(F)cc(F)c1

InChI Key InChIKey=STJVJNLIORNEOD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342937   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM342937(1-(6-cyano-3',5'-difluoro-4-methoxy-3-biphenylyl)-...)
Affinity DataIC50:  9.11E+3nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent