BDBM343010 4-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-pyridazinyl-7-quinazolinesulfonamide::US9776995, Example 15

SMILES COc1cc(c(Cl)cc1-c1ncnc2cc(ccc12)S(=O)(=O)Nc1cccnn1)-c1cccc(F)c1

InChI Key InChIKey=JLIWZAHVAKRWQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343010   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM343010(4-(2-chloro-3'-fluoro-5-methoxy-4-biphenylyl)-N-3-...)
Affinity DataIC50:  110nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent