BDBM343113 1-(3'-chloro-4'-fluoro-5-methoxy-2-methyl-4-biphenylyl)-N-3-isoxazolyl-6-isoquinolinesulfonamide::US9776995, Example 284

SMILES COc1cc(c(C)cc1-c1nccc2cc(ccc12)S(=O)(=O)Nc1ccon1)-c1ccc(F)c(Cl)c1

InChI Key InChIKey=FJPHYRGCIXZIJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343113   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM343113(1-(3'-chloro-4'-fluoro-5-methoxy-2-methyl-4-biphen...)
Affinity DataIC50:  22.8nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent