BDBM3433 1-[2-amino-6-(2,6-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea::6-arylpyrido[2,3-d]pyrimidine deriv. 15::CHEMBL57323::PD089828 analog 15

SMILES: Cc1cccc(C)c1-c1cc2cnc(N)nc2nc1NC(=O)NC(C)(C)C

InChI Key: InChIKey=GQMZTFFTTCUZAW-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 3433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Human)	BDBM3433 (6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	7.4	25
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Fibroblast growth factor receptor 1 (Human)	BDBM3433 (6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	7.4	25
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM3433 (6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	7.4	25
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					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM3433 (6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Human)	BDBM3433 (6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM3433 (6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Human)	BDBM3433 (6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM3433 (6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3433 (6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM3433 (6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair