BDBM3436 6-(2,6-Dibromo-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine::6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine::6-arylpyrido[2,3-d]pyrimidine deriv. 18::ACS Chem. Biol. Compound 1

SMILES: Nc1ncc2cc(c(N)nc2n1)-c1c(Br)cccc1Br

InChI Key: InChIKey=HGIPWJYTPOHUGK-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Human)	BDBM3436 (6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM3436 (6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM3436 (6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Biotin carboxylase (Escherichia coli (strain K12))	BDBM3436 (6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	8.0	23
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Biotin carboxylase (Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)	BDBM3436 (6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
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