BDBM343678 3-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-yl]oxy}-N-(propan-2-yl)propan-1-amine::US9777004, 9

SMILES CC(C)NCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1

InChI Key InChIKey=BHAGDZVLGOTYEF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343678   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM343678(3-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50:  20nMAssay Description:For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM343678(3-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50:  7nMAssay Description:For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent