BDBM3441 1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea::6-arylpyrido[2,3-d]pyrimidine deriv. 23::CHEMBL56236::PD162628

SMILES: Cc1cc(C)c(C)c(c1C)-c1cc2cnc(N)nc2nc1NC(=O)NC(C)(C)C

InChI Key: InChIKey=NNYHIJGVHOAIGK-UHFFFAOYSA-N

Data: 15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 3441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	25
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Fibroblast growth factor receptor 1 (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1/3 (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Insulin receptor (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM3441 (1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair