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BDBM34437 (6Z)-6-[(4-methylpiperidin-1-yl)-sulfanyl-methylidene]cyclohexa-2,4-dien-1-one::(6Z)-6-[(4-methylpiperidin-1-yl)-sulfanylmethylidene]cyclohexa-2,4-dien-1-one::(6Z)-6-[mercapto-(4-methyl-1-piperidinyl)methylidene]-1-cyclohexa-2,4-dienone::(6Z)-6-[mercapto-(4-methylpiperidino)methylene]cyclohexa-2,4-dien-1-one::2-[(4-methyl-1-piperidinyl)carbonothioyl]phenol::MLS000049665::SMR000076278::cid_5739595

SMILES: CC1CCN(CC1)C(=S)c1ccccc1O

InChI Key: InChIKey=MYTNDQBMUZXFAA-UHFFFAOYSA-N

Data: 2 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34437   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
eukaryotic translation initiation factor 4 gamma, 1 isoform 4


(Homo sapiens (Human))
BDBM34437
PNG
((6Z)-6-[(4-methylpiperidin-1-yl)-sulfanyl-methylid...)
Show SMILES CC1CCN(CC1)C(=S)c1ccccc1O
Show InChI InChI=1S/C13H17NOS/c1-10-6-8-14(9-7-10)13(16)11-4-2-3-5-12(11)15/h2-5,10,15H,6-9H2,1H3
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
PCBioAssay
n/an/a 6.40E+4n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2RN3686
More data for this
Ligand-Target Pair
Gag-Pol polyprotein


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM34437
PNG
((6Z)-6-[(4-methylpiperidin-1-yl)-sulfanyl-methylid...)
Show SMILES CC1CCN(CC1)C(=S)c1ccccc1O
Show InChI InChI=1S/C13H17NOS/c1-10-6-8-14(9-7-10)13(16)11-4-2-3-5-12(11)15/h2-5,10,15H,6-9H2,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/a 6.11E+3n/an/an/an/a8.023



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H70D5W
More data for this
Ligand-Target Pair